I wrote this song a long time ago seeing someone's dark brown eyes and now I realized very few fully appreciated the song because the nobody fully understood it. For those not belonging to the non medical fraternity I am writing this explanation. Please give feed back.
if you haven't read the song please refer the previous post on the blog. http://psychomore.blogspot.in/2011/01/doctors-love-song-aka-drug-of-choice.html
Lugol's iodine is a dark brown coloured solution (colour of someone's
eyes) containing potassium iodide and elemental iodine.
Thyroid storm is an emergency condition triggered by an infection in an
hyper thyroid patient causing high fever, increased heart rate, restlessness
etc.
Lugol's
iodine acts on the thyroid gland and reduces the production of thyroid hormone
also it reduces the blood supply to the gland and makes the gland firmer hence
easier to operate upon.That is why even though there are other drugs available I prefer Lugol's iodine.One more thing lugol's iodine can only be given for a 5-7 days if given
for a longer period it causes an increase in thyroid hormone worsening the
condition.
P.falciparum
is the only strain of the 4 found that has a gene which gives it resistance
against chloroquine.In addition, it's life cycle is a bit different than the
others so it is more invasive.It can also cause cerebral malaria
which is fatal.Quinine acts like a magic drug against this type showing
response from the first dose itself and hence it is reserved for treatment of
chloroquine resistant malaria.
Though
resistance to quinine was also seen due to indiscriminate use.It's use was
stopped for some time ,the stopping caused the organisms to be sensitive to it
again and so it remains the most economic drug.Though it can cause destruction
of RBC's causing the haemoglobin to be excreted in urine giving it a black
colour which is known as "black water fever".
Anaphylaxis
is a severe type of allergic reaction.There is a massive release of histamine
which causes blood vessels to dilate and the blood pressure to drop leading to
shock, it also causes oedema (swelling) and sometimes out can also cause
laryngeal oedema so the airway gets blocked making it impossible to breathe.In
such a serious scenario only drug that can act quick enough is adrenaline which
constricts the blood vessels, increases the blood pressure, reduces the oedema
and opens the airway like giving one more breath to a drowning man.
But
it is a very risky to administer because if not properly diluted it can cause
arrhythmia (irregular heart beat) ,convulsions and ultimately Death.
Hypertensive
crisis is the rise in blood pressure above 160/100 mmHg with possibility of
damage to organs.It is requires immediate medical attention as intravenous
drugs have to be started as soon as possible.Rarely is it possible to reach the
hospital on time and for this there needs to be an alternative is a drug that
can be administered by a layman and acts quickly. Right now the only one
available is sublingual Nifedipine.Though there is a big controversy about it's
use because of irregular absorption and causing cerebral steal(stealing blood supply from the brain) by pooling of blood in the
extremities and its use for hypertensive crisis has been banned in some
countries but in India I have seen it being used that too effectively so for me
it remains the drug of choice.
The
above mentioned drugs have a major action on heart and can kill the heart
muscle i.e. cause cardiotoxicity if not used in proper way.hence they are
classified under schedule H and to be taken under supervision of a registered
medical practitioner.
Similarly Love is a drug , even though it has its adverse effects and side effects , some of which are unavoidable, at times it is life saving.
In other words : One man's MEDICINE is another man's POISON.
