Saturday, June 23, 2012

Explanation for "Doctor's Love Song aka Drug of Choice"


I wrote this song a long time ago seeing someone's dark brown eyes and now I realized very few fully appreciated the song because the nobody fully understood it. For those not belonging to the non medical fraternity I am writing this explanation. Please give feed back.
if you haven't read the song please refer the previous post on the blog. http://psychomore.blogspot.in/2011/01/doctors-love-song-aka-drug-of-choice.html




Lugol's iodine is a dark brown coloured solution (colour of someone's eyes) containing potassium iodide and elemental iodine.
Thyroid storm is an emergency condition triggered by an infection in an hyper thyroid patient causing high fever, increased heart rate, restlessness etc.
Lugol's iodine acts on the thyroid gland and reduces the production of thyroid hormone also it reduces the blood supply to the gland and makes the gland firmer hence easier to operate upon.That is why even though there are other drugs available I prefer Lugol's iodine.One more thing lugol's iodine can only be given for a 5-7 days if given for a longer period it causes an increase in thyroid hormone worsening the condition.

P.falciparum is the only strain of the 4 found that has a gene which gives it resistance against chloroquine.In addition, it's life cycle is a bit different than the others so it is more invasive.It can also cause cerebral malaria which is fatal.Quinine acts like a magic drug against this type showing response from the first dose itself and hence it is reserved for treatment of chloroquine resistant malaria.
Though resistance to quinine was also seen due to indiscriminate use.It's use was stopped for some time ,the stopping caused the organisms to be sensitive to it again and so it remains the most economic drug.Though it can cause destruction of RBC's causing the haemoglobin to be excreted in urine giving it a black colour which is known as "black water fever".

Anaphylaxis is a severe type of allergic reaction.There is a massive release of histamine which causes blood vessels to dilate and the blood pressure to drop leading to shock, it also causes oedema (swelling) and sometimes out can also cause laryngeal oedema so the airway gets blocked making it impossible to breathe.In such a serious scenario only drug that can act quick enough is adrenaline which constricts the blood vessels, increases the blood pressure, reduces the oedema and opens the airway like giving one more breath to a drowning man.
But it is a very risky to administer because if not properly diluted it can cause arrhythmia (irregular heart beat) ,convulsions and ultimately Death.

Hypertensive crisis is the rise in blood pressure above 160/100 mmHg with possibility of damage to organs.It is requires immediate medical attention as intravenous drugs have to be started as soon as possible.Rarely is it possible to reach the hospital on time and for this there needs to be an alternative is a drug that can be administered by a layman and acts quickly. Right now the only one available is sublingual Nifedipine.Though there is a big controversy about it's use because of irregular absorption and causing cerebral steal(stealing blood supply from the brain) by pooling of blood in the extremities and its use for hypertensive crisis has been banned in some countries but in India I have seen it being used that too effectively so for me it remains the drug of choice.

The above mentioned drugs have a major action on heart and can kill the heart muscle i.e. cause cardiotoxicity if not used in proper way.hence they are classified under schedule H and to be taken under supervision of a registered medical practitioner.

Similarly Love is a drug , even though it has its adverse effects and side effects , some of which are unavoidable, at times it is life saving. 

In other words : One man's MEDICINE is another man's POISON.

No comments:

Post a Comment